Virecta 50mg

PROPERTIES

Virecta is a safe and effective oral treatment for erectiledysfunction (ED) in men. ED is the persistent inability to achieve or sustain an erection sufficient for satisfactory sexual performance, a satisfactory treatment for this condition relies on the relaxation of the smooth muscles of the corpora carvernosa to facilitate erection. Sildenafil citrate is a selective inhibitor of type V phosphodiesterase (PDE5) that enhances the effect of nitric oxide (NO) which is released in the corpora in response to sexual stimulation. The release of NO stimulates the enzyme guanylate cyclase to produce cyclic GMP, which in turn relaxes arterial smooth muscle. Cyclic GMP is then broken down by PDE5. Sildenafil as a PDE5 inhibitor prevents the breakdown of cyclic GMP and hence prolongs arterial relaxation and inflow of arterial blood and thereby enhances erection. Virecta therefore causes erection only in the context of sexual stimulation.

INDICATIONS

For the treatment of erectile dysfunction.

CONTRA-INDICATION

In patients with known hypersensitivity to sildenafil or any of the components of the tablet.

In patients who are using organic nitrates, concomitant therapy with Virecta may potentiate the hypotensive effect of nitrates.

Not indicated for use in newborn, children or women.

In patients with pre-existing cardiovascular disease and those having atrophy of the optical nerve and decreased visual field.

Prolonged erection greater than 4 hours (painful erection greater than 6 hours in duration) the patient should seek immediate medical assistance .If priapism is not treated immediately; penile tissue damage and permanent loss of potency could result.

SIDE EFFECTS

With the prescribed dosage, the most common side effects, which are only mild to moderate and usually do not last longer than a few hours are:
headache, flushing of the face, dyspepsia, nasal congestion and to a lesser extent urinary tract infection, mild and transient color tinge to vision, sensitivity to light or blurred vision, diarrhea, dizziness and rash.

Other minor adverse effects that are less common and are not likely to occur are:
Vomiting, glossitis, colitis, dysphagia, gastritis, gastroenteritis, stomatitis, dry mouth, abnormal liver function tests, rectal hemorrhage, gingivitis.

Edema of the face, photosensitivity reaction, shock, asthenia, chills, abdominal pain, allergic reaction, chest pain.

Angina pectoris, AV block, migraine, syncope, tachycardia, palpitation, postural hypertension, myocardial ischemia, cerebral thrombosis, cardiac arrest, heart failure, abnormal electrocardiogram, cardiomyopathy. Arthritis, arthrosis, myalgia, tendon rupture, tenosynovitis, bone pain, myasthenia and synovitis.

Anemia and leucopenia. Thirst, edema, gout, diabetes, hyperglycemia, peripheral edema, hyperuricemia, hypoglycemic reactions, hypernatremia. Ataxia, hypertonia, neuralgia, neuropathy, paresthesia, tremor, vertigo, depression, insomnia, somnolence, decreased reflexes and hypesthesia. Asthma, dyspnea, laryngitis, pharyngitis, sinusitis, bronchitis, increased sputum and cough.

Urticaria, herpes simplex, pruritus, sweating, ulcer, contact & exfoliative dermatitis. Mydriasis, conjunctivitis, photophobia, tinnitus, eye pain, deafness, ear pain, hemorrhage, cataract, dry eyes. Cystitis, nocturia, urinary frequency, breast enlargement, urinary incontinence, abnormal ejaculation, general edema and anorgasmia.